Katja Brueckner, PhD

Department of Cell & Tissue Biology
+1 415 476-3827

Katja Brueckner received her PhD. in biology and cell signalling from the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany. She performed her postdoctoral studies at the EMBL and Harvard Medical School. Katja was a Howard Hughes Medical Institute Associate, long-term post-doctoral fellow of the European Molecular Biology Organization (EMBO) and Human Frontier Science Program (HFSP), and Special Fellow of the Leukemia & Lymphoma Society (LLS). For her post-doctoral studies, the LLS awarded Katja with the Brian P. ODell Memorial Research Award. Since joining the faculty of UCSF in late 2006, Katja has received a Hellman Family Scholar Award, an American Cancer Society Research Scholar Award, an American Heart Association career development award, and she is funded by research grants from the National Science Foundation and the National Institutes of Health.

Research Summary: 
Hematopoiesis and cell signaling



Assaying blood cell populations of the Drosophila melanogaster larva

Journal of Visualized Experiments (JoVE)

Petraki, S., Alexander, B., Brückner, K..

Arginine Methylation Initiates BMP-Induced Smad Signaling.

Molecular cell

Xu J, Wang AH, Oses-Prieto J, Makhijani K, Katsuno Y, Pei M, Yan L, Zheng YG, Burlingame A, Brückner K, Derynck R

Schnurri regulates hemocyte function to promote tissue recovery after DNA damage.

Journal of cell science

Kelsey EM, Luo X, Brückner K, Jasper H

The peripheral nervous system supports blood cell homing and survival in the Drosophila larva.

Development (Cambridge, England)

Makhijani K, Alexander B, Tanaka T, Rulifson E, Brückner K

Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.

PLoS genetics

Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N

The PDGF/VEGF receptor controls blood cell survival in Drosophila.

Developmental cell

Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N

The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.

EMBO reports

Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.


Brückner K, Perez L, Clausen H, Cohen S

EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains.


Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R

Signaling by Eph receptors and their ephrin ligands.

Current opinion in neurobiology

Brückner K, Klein R

Tyrosine phosphorylation of transmembrane ligands for Eph receptors.

Science (New York, N.Y.)

Brückner K, Pasquale EB, Klein R

Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors.

Molecular and cellular neurosciences

Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R