Deepak Lamba, PhD

Associate Professor
Ophthalmology
+1 415 502-4969

The lab focuses on retinal repair and disease modeling using human stem cell technologies and organoid systems. The key focus areas include (1) exploring the potential and challenges in retinal cell replacement therapies esp. the role of the tissue microenvironment and (2) using  stem-cell based model systems to understand various human retinal degenerations and identify new therapeutic avenues including genome editing technologies like CRISPR.

Websites

Featured Publications: 

Immune modulation by MANF promotes tissue repair and regenerative success in the retina.

Science (New York, N.Y.)

Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, Chew S, Qi Y, Jasper H, Lamba DA

MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage.

Nature metabolism

Sousa-Victor P, Neves J, Cedron-Craft W, Ventura PB, Liao CY, Riley RR, Soifer I, van Bruggen N, Kolumam GA, Villeda SA, Lamba DA, Jasper H