DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.
The Wednesday Journal Club (formerly Developmental Biology) takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.
The Friday Journal Club (formerly Stem Cell) takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.
DSCB Journal Club Chair: Dan Wagner, PhD
The Zoom link and meeting password will be sent out to those on the DSCB listservs the day of every journal club. Please contact Meredith Miner if you are not already on one of our listservs.
2023-24 Schedule
Friday, October 6, 2023 - 11:30am - Room: N-217
Christopher He (student)
"A Stem Cell Zoo: developmental tempo across species"
Lázaro, Jorge, et al. "A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals." Cell Stem Cell (2023). https://doi.org/10.1016/j.stem.2023.05.014
Coaches: Mustafa Aydogan, PhD & Dan Wagner, PhD
Wednesday, October 11, 2023 - 5pm - Room: MH-1407
Nitya Kopparapu (student)
TBD
Korkmazhan, E., & Dunn, A. R. (2022). The membrane-actin linker ezrin acts as a sliding anchor. Science Advances, 8(31). https://doi.org/10.1126/sciadv.abo2779
Friday, October 27, 2023 - 12pm - Room: N-217
Jonathan Ramirez (student)
TBD
McNamara, H. M., Solley, S. C., Adamson, B., Chan, M. M. & Toettcher, J. E. Recording morphogen signals reveals origins of gastruloid symmetry breaking. http://biorxiv.org/lookup/doi/10.1101/2023.06.02.543474 (2023) doi:10.1101/2023.06.02.543474.
Coaches: Orion Weiner, PhD & Dan Wagner, PhD
Wednesday, November 1, 2023 - 5pm - Room: MH-1407
Andrew Cesiulis (student)
"Single-cell brain organoid screening identifies developmental defects in autism"
Li, C., Fleck, J.S., Martins-Costa, C. et al. Single-cell brain organoid screening identifies developmental defects in autism. Nature 621, 373–380 (2023). https://doi.org/10.1038/s41586-023-06473-y
Wednesday, November 15, 2023 - 5pm - Room: MH-1407
Francesco Dalla Ricca (student)
"IE Human Embryos Models: big potential and even bigger ethical questions"
Oldak, B., Wildschutz, E., Bondarenko, V. et al. Complete human day 14 post-implantation embryo models from naive ES cells. Nature 622, 562–573 (2023). https://doi.org/10.1038/s41586-023-06604-5
Friday, November 17, 2023 - 12pm - Room: N-217
Elphege Nora (faculty)
"Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus"
Gjaltema et al., Molecular Cell https://www.sciencedirect.com/science/article/pii/S109727652101025X?via%3Dihub
Adriana Guajardo (student)
"Senescence is the essence of whole-body regeneration in cnidarians"
Salinas-Saavedra M, Febrimarsa, Krasovec G, Horkan HR, Baxevanis AD, Frank U. Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration. Cell Rep. 2023 Jul 25;42(7):112687. doi: 10.1016/j.celrep.2023.112687. Epub 2023 Jun 30.
Coaches: David Booth, PhD & Mercedes Paredes, MD, PhD
Friday, December 8, 2023 - 12pm - Room: N-217
Licia Selleri (faculty)
“Assembling Head Structures by Remote Control”
Kessler S, Minoux M, Joshi O, Ben Zouari Y, Ducret S, Ross F, Vilain N, Salvi A, Wolff J, Kohler H, Stadler MB, Rijli FM. “A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest.” Nat Commun. 2023 Jun 5;14(1):3242. doi: 10.1038/s41467-023-38953-0.
Elysse Phillips (student)
“Reciprocal cell-ECM dynamics generate supracellular fluidity underlying spontaneous follicle patterning”
Palmquist, Karl H., Sydney F. Tiemann, Farrah L. Ezzeddine, Sichen Yang, Charlotte R. Pfeifer, Anna Erzberger, Alan R. Rodrigues, and Amy E. Shyer. 2022. “Reciprocal Cell-ECM Dynamics Generate Supracellular Fluidity Underlying Spontaneous Follicle Patterning.” Cell 185 (11): 1960–73.e11.
Coaches: Dan Wagner, PhD & Matt Kutys, PhD
Wednesday, January 17, 2024 - 5pm - Room: MH-1407
Nicole Suren (student)
"Transplantation of human cortical organoids into rats results in integration of human neurons into rat brain circuits and subsequent behavioral changes"
Revah, O., Gore, F., Kelley, K.W. et al. Maturation and circuit integration of transplanted human cortical organoids. Nature 610, 319–326 (2022). https://doi.org/10.1038/s41586-022-05277-w
Friday, January 19, 2024 - 12pm - Room: N-217
David Wen (student)
"Base Editors Break Basic Blood Biology."
Martin-Rufino JD, et al. Massively parallel base editing to map variant effects in human hematopoiesis. Cell. 2023 May 25;186(11):2456-2474.e24. doi: 10.1016/j.cell.2023.03.035. Epub 2023 May 2. PMID: 37137305; PMCID: PMC10225359.
Coaches: Kyle Cromer, PhD & Martin Kampmann, PhD
Cindy Ow (student)
TBD
Hyojeong Hwang, Sijie Chen, Meng Ma, Divyanshi, Hao-Chun Fan, Elizabeth Borwick, Elvan Böke, Wenyan Mei, Jing Yang, Solubility phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition, Developmental Cell, 2023 DOI: 10.1016/j.devcel.2023.10.005 https://www.cell.com/developmental-cell/fulltext/S1534-5807(23)00524-5
Coaches: Todd Nystul, PhD & Erica Hutchins, PhD
Friday, February 16, 2024 - 12pm - Room: N-217
Rose Zhou (student)
"Neurogenesis in Mothers"
Chaker, Zayna, et al. "Pregnancy-responsive pools of adult neural stem cells for transient neurogenesis in mothers." Science 382.6673 (2023): 958-963.
Coaches: Dan Wagner, PhD & Mercedes Paredes, MD, PhD
Vasileios Papakis (student)
"Unraveling the Role of Oligodendrocyte Precursor Cell Glutamate Signaling in Development and Regeneration"
Khawaja, R. R., Agarwal, A., Fukaya, M., Jeong, H.-K., Gross, S., Gonzalez-Fernandez, E., Soboloff, J., Bergles, D. E., & Kang, S. H. (2021). GLUA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration. Cell Reports, 35(7), 109147. https://doi.org/10.1016/j.celrep.2021.109147
Coaches: Stephen Fancy, PhD, DVM & Trent Watkins, PhD
Wednesday, March 6, 2024 - 5pm - Room: MH-1407
Tayma Handal (student)
"Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice"
Takahashi Y, Morales Valencia M, Yu Y, Ouchi Y, Takahashi K, Shokhirev MN, Lande K, Williams AE, Fresia C, Kurita M, Hishida T, Shojima K, Hatanaka F, Nuñez-Delicado E, Esteban CR, Izpisua Belmonte JC. Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice. Cell. 2023 Feb 16;186(4):715-731.e19. doi: 10.1016/j.cell.2022.12.047. Epub 2023 Feb 7. PMID: 36754048.
Friday, March 15, 2024 - 12pm - Room: HSW-302
Ricardo Espinosa Lima (student)
"Too Hot or Too Cold: Homeostatic Control of ECM Through Yap/Taz Mechanoepigenomics"
Jones, Dakota L., et al. "Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz." Proceedings of the National Academy of Sciences 120.22 (2023): e2211947120.
Coaches: Kelsey Collins, PhD & Alexis Dang, MD
Nicole Suren (student)
"Complex morphogen signaling: Cytoneme-mediated transport of active Wnt-PCP complexes"
Zhang, C., Brunt, L., Ono, Y. et al. Cytoneme-mediated transport of active Wnt5b–Ror2 complexes in zebrafish. Nature 625, 126–133 (2024). https://doi.org/10.1038/s41586-023-06850-7
Coaches: Dan Wagner, PhD & Jeff Bush, PhD
Friday, April 12, 2024 - 12pm - Room: N-217
Tayma Handal (student)
TBD
Tam, P.L.F., Cheung, M.F., Chan, L.Y. et al. Cell-type differential targeting of SETDB1 prevents aberrant CTCF binding, chromatin looping, and cis-regulatory interactions. Nat Commun 15, 15 (2024). https://doi.org/10.1038/s41467-023-44578-0
Coaches: Elphege Nora, PhD & Faranak Fattahi, PhD
Francesco Dalla Ricca (student)
TBD
Friday, May 10, 2024 - 12pm - Room: N-217
Andrew Cesiulis (student)
TBD
Nitya Kopparapu (student)
TBD