
Assistant Professor
M_Biochemistry and Biophysics
+1 415 921-9772
With a combination of molecular genetics, biochemistry, functional genomics, and cell biology, we are exploring the molecular mechanisms and environmental cues that govern the transitions between different choanoflagellates cell types.
Research Summary
With a combination of molecular genetics, biochemistry, functional genomics, and cell biology, we are exploring the molecular mechanisms and environmental cues that govern the transitions between different choanoflagellates cell types.
Publications
Cell differentiation controls iron assimilation in the choanoflagellate Salpingoeca rosetta.
mSphere
Cell differentiation controls iron assimilation in a choanoflagellate.
bioRxiv : the preprint server for biology
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating transposons and cell type-specific genes in choanoflagellates.
bioRxiv : the preprint server for biology
A red algal polysaccharide influences the multicellular development of the choanoflagellate Salpingoeca rosetta.
bioRxiv : the preprint server for biology
An RFX transcription factor regulates ciliogenesis in the closest living relatives of animals.
Current biology : CB
Cell polarity in the protist-to-animal transition.
Current topics in developmental biology
The history of Salpingoeca rosetta as a model for reconstructing animal origins.
Current topics in developmental biology
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.
PLoS pathogens
Genetic tool development in marine protists: emerging model organisms for experimental cell biology.
Nature methods
Transfection of choanoflagellates illuminates their cell biology and the ancestry of animal septins.
Molecular biology of the cell
A structurally plastic ribonucleoprotein complex mediates post-transcriptional gene regulation in HIV-1.
Wiley interdisciplinary reviews. RNA
Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.
Molecular and cellular biology
Fabs enable single particle cryoEM studies of small proteins.
Structure (London, England : 1993)
Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition.
Journal of visualized experiments : JoVE
HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes.
Proceedings of the National Academy of Sciences of the United States of America
Signal sequences activate the catalytic switch of SRP RNA.
Science (New York, N.Y.)