DSCB 216 Journal Club

DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.

The Wednesday Journal Club (formerly Developmental Biology) takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.

The Friday Journal Club (formerly Stem Cell) takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.

DSCB Journal Club Chairs: Dan Wagner, PhD and >Kelsey H. Collins, PhD

The Zoom link and meeting password will be sent out to those on the DSCB listservs the day of every journal club. Please contact Meredith Miner if you are not already on one of our listservs.

2025-26 Journal Club Schedule

 Chris Hsiung, MD, PhD (faculty)

"Latent functions of the non-coding genome in tissue injury responses"

Lin W, Jia X, Shi X, He Q, Zhang P, Zhang X, Zhang L, Wu M, Ren T, Liu Y, Deng H, Li Y, Liu S, Huang S, Kang J, Luo J, Deng Z, Wang W. Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch. Science. American Association for the Advancement of Science (AAAS); 2025 Jun 26;388(6754):eadp0176. PMID: 40570123

Edward Valenzuela (student)

"Long-range cholinergic input promotes glioblastoma progression"

Yang, Y., Yang, C., Chen, X., Jiang, Y., Lei, X., Ma, K., Quan, Y., Li, T., Guo, C., Meng, Y., et al. (2025). Long-range cholinergic input promotes glioblastoma progression. Cancer Cell. 10.1016/j.ccell.2025.07.024.

Moderators: Brindha Rathinasabapathi and Feeling Chen

Location: Room S-214, Parnassus; Viewing Room (for senior students and faculty ONLY) located in MH-1405

 

Gabriel Avillion (student)

TBD

Jeffries, A.M., Yu, T., Ziegenfuss, J.S. et al. Single-cell transcriptomic and genomic changes in the ageing human brain. Nature (2025). Https://doi.org/10.1038/s41586-025-09435-8

Coaches: Andrew Yang, PhD and Kristen Berendzen, MD, PhD

Naomi Cinque (student)

"Distinct adipose progenitor cells emerging with age drive active adipogenesis"

Guan Wang et al., Distinct adipose progenitor cells emerging with age drive active adipogenesis. Science388,eadj0430(2025). DOI:10.1126/science.adj0430

Coaches: Kyle Cromer, PhD and Ed Hsiao, MD, PhD

Moderators: Bivas Nag and Carine Joubran

Location: HSW-302, Parnassus; Viewing Room (for senior students and faculty ONLY) located in MH-1405

Max Hammer (student)

"Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation"

Basso M, Mahuzier A, et al. Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation. Dev Cell. 2025 Mar 10;60(5):749-761.e5. doi: 10.1016/j.devcel.2024.11.008. Epub 2024 Dec 10.

 

Ashley Fox (student)

"Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis"

Edwards, N. A., Rankin, S. A.et al (2025). Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis. Developmental cell, 60(18), 2487–2502.e4. https://doi.org/10.1016/j.devcel.2025.04.026

Location: MH-1407, Mission Bay

Gabriella Cox (student)

"Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells"

Toulouse, G., Jarassier, W., Jagot, S., Morin, V., Le Grand, F., & Marcelle, C. (2025). Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells. Nature communications, 16(1), 7858. https://doi.org/10.1038/s41467-025-61767-1 

 

Daniel Bernstein (student)

"Actomyosin forces trigger a conformational change in desmoplakin within desmosomes"

Dong, Y., Elgerbi, A., Xie, B. et al. Actomyosin forces trigger a conformational change in desmoplakin within desmosomes. Nat Commun 16, 9052 (2025). https://doi.org/10.1038/s41467-025-64124-4

Location: MH-1407, Mission Bay

Bivas Nag (Student)

"3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy"

Zhang, Xinyue et al. Cell Stem Cell, Volume 32, Issue 11, 1758 - 1772.e8

Coaches: Alex Pollen, PhD and Corey Harwell, PhD

Carine Joubran (Student)

"Myocardium and endocardium of the early mammalian heart tube arise from independent multipotent lineages specified at the primitive streak"

Sendra, Miquel et al. Developmental Cell, Volume 60, Issue 18, 2434 - 2444.e5 DOI: 10.1016/j.devcel.2025.05.002

Coaches: Faranak Fattahi, PhD and Benoit Bruneau, PhD

Moderators: Gabriel Avillion and Naomi Cinque

Location: HSW-302, Parnassus; Viewing Room (for senior students and faculty ONLY) located in MH-1405

Annie Adachi (Student)

“Range extender mediates long-distance enhancer activity.”

Bower, G., Hollingsworth, E.W., Jacinto, S.H. et al. Range extender mediates long-distance enhancer activity. Nature 643, 830–838 (2025). https://doi.org/10.1038/s41586-025-09221-6

Lea Baskin Monk (Student)

"Evidence for improved DNA repair in long-lived bowhead whale"

Firsanov, D., Zacher, M., Tian, X. et al. Evidence for improved DNA repair in long-lived bowhead whale. Nature (2025). https://doi.org/10.1038/s41586-025-09694-5

Location: MH-1407, Mission Bay

Brindha Rathinasabapathi (student)

"Dissecting Epigenetic Regulation of Fibrosis in Heart Disease"

Aguado-Alvaro, L.P., Garitano, N., Esser-Skala, W. et al. Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens.Nat Commun 16, 11660 (2025). 

Coaches: Todd Nystul, PhD and Michael Alexanian, PhD

Feeling Chen (student)

"Repair of DNA double-strand breaks leaves heritable impairment to genome Function"

Susanne Bantele et al.,Repair of DNA double-strand breaks leaves heritable impairment to genome function.Science390,eadk6662(2025).DOI:10.1126/science.adk6662

Coaches: Kelsey Collins, PhD and Saul Villeda, PhD

Moderators: Edward Valenzuela and Patrick Taylor

Location: HSW-300, Parnassus

Patrick Taylor (student)

"Radial astroglia cooperate with microglia to clear neuronal cell bodies during zebrafish optic tectum development"

Barber, Heather M., et al. 2025. “Radial Astroglia Cooperate with Microglia to Clear Neuronal Cell Bodies during Zebrafish Optic Tectum Development.” Cell Reports 44 (11): 116509.

Sarah Soliman (student)

"Tissue fluidity mediates a trade-off between the speed and accuracy of multicellular patterning by cell sorting"

Garner, Rikki M. et al. Tissue fluidity mediates a trade-off between the speed and accuracy of multicellular patterning by cell sorting. Biophysical Journal, Volume 124, Issue 23, 4157 - 4175. doi.org/10.1016/j.bpj.2025.10.001

Location: MH-1407, Mission Bay

Patrick Taylor (student)

TBD

Sarah Soliman (student)

TBD

Moderators: Tiffany Pham and Olivia Sclafani

Location: HSW-300, Parnassus

Tiffany Pham (student)

TBD

Olivia Sclafani (student)

TBD

Location: MH-1407, Mission Bay

Tiffany Pham (student)

TBD

Annie Adachi (student)

TBD

Moderators: Vincent Ling and Anush Margaryan

Location: HSW-300, Parnassus

Vincent Ling (student)

TBD

Anush Margaryan (student)

TBD

Location: MH-1407, Mission Bay

Vincent Ling (student)

TBD

Anush Margaryan (student)

TBD

Moderators: Ashley Fox and Max Hammer

Location: HSW-300, Parnassus

Ashley Fox (student)

TBD

Max Hammer (student)

TBD

Moderators: Daniel Bernstein and Gabriella Cox

Location: HSW-302, Parnassus

Student: TBD

Student: TBD

Location: MH-1407, Mission Bay

Student: TBD

Student: TBD

Location: MH-1407, Mission Bay

Daniel Bernstein (student)

TBD

Gabriella Cox (student)

TBD

Moderators: Annie Adachi and Lea Baskin Monk

Location: HSW-302, Parnassus

Olivia Sclafani (student)

TBD

Lea Baskin Monk (student)

TBD

Moderators: Sarah Soliman

Location: HSW-302, Parnassus