Assistant Professor
P_Bioengineering
Our lab’s research focus is on developing and applying impactful genomic technologies toward understanding gene regulation underlying development and human diseases.
Publications
A multiplex, prime editing framework for identifying drug resistance variants at scale.
Cell genomics
Large-scale discovery of neural enhancers for cis-regulation therapies.
bioRxiv : the preprint server for biology
Single-cell, multi-region profiling of the macaque brain across the lifespan.
bioRxiv : the preprint server for biology
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
Nature communications
Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters.
Nature methods
Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements.
bioRxiv : the preprint server for biology
Chromatin context-dependent regulation and epigenetic manipulation of prime editing.
bioRxiv : the preprint server for biology
The continuum of Drosophila embryonic development at single-cell resolution.
Science (New York, N.Y.)
Ancient Rome: A genetic crossroads of Europe and the Mediterranean.
Science (New York, N.Y.)
Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression.
American journal of human genetics
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system.
Proceedings of the National Academy of Sciences of the United States of America