Professor, Anatomy
Director, Bakar Aging Research Institute Anatomy
M_Anatomy
+1 415 476-4622
The Jones Lab primary goal is characterizing fundamental mechanisms that are involved in regulating stem cell behavior. Once such mechanisms are established, we are interested in understanding how these mechanisms are altered by organismal aging or chronic or acute changes in metabolism, leading to age-onset diseases, such as cancer.
Research Summary
Defining conserved mechanisms regulating stem cell behavior and how these are altered with age and in response to chronic or acute changes in metabolism.
Websites
Publications
Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging.
Cold Spring Harbor perspectives in biology
Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor.
Stem cell reports
DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging.
Cellular and molecular gastroenterology and hepatology