Circulation

Abstract 4140108: A CRISPR-Activation CROP-seq Screen Identifies HMGN1 as a Dosage-Sensitive Regulator of Heart Defects in Down Syndrome.

Circulation

Sanjeev Ranade, Feiya Li, Sean Whalen, Pelonero Angelo, Lin Ye, Yu Huang, Abigail Brand, Tomohiro Nishino, Mauro Costa, Rahul Mital, Ryan Boileau, Frances Koback, Arun Padmanabhan, Alexander Merriman, Langley Wallace, Annie Nguyen, Nikolaus Poulis, Casey Gifford, Katherine Pollard, Deepak Srivastava

Improved Cardiac Function in Postischemic Rats Using an Optimized Cardiac Reprogramming Cocktail Delivered in a Single Novel Adeno-Associated Virus.

Circulation

Zhou H, Yang J, Srinath C, Zeng A, Wu I, Leon EC, Qureshi TN, Reid CA, Nettesheim ER, Xu E, Duclos Z, Mohamed TMA, Farshidfar F, Fejes A, Liu J, Jones S, Feathers C, Chung TW, Jing F, Prince WS, Lin J, Yu P, Srivastava D, Hoey T, Ivey KN, Lombardi LM

Abstract 14797: Single Cell Multi-Modal Analyses Reveal Epigenomic and Transcriptomic Basis Underlying Cardiac Defects in Maternal Diabetes.

Circulation

Tomohiro Nishino, Sanjeev Ranade, Pelonero Angelo, Benjamin J van Soldt, Lin Ye, Michael Alexanian, Frances Koback, Yu Huang, Nandhini Sadagopan, Arun Padmanabhan, Reuben Thomas, Joke van Bemmel, Casey Gifford, Mauro Costa, Deepak Srivastava

Abstract 13625: Autophagy Plays a Key Role in the Loss of Nitric Oxide Signaling and Endothelial Dysfunction in Pulmonary Vascular Diseases.

Circulation

Ying Liang, Wojciech Ornatowski, Qing Lu, Xutong Sun, Alejandro E Garcia, Evgeny A Zemskov, Emin Maltepe, Jeffrey R Fineman, Kim Tieu, Ting Wang, Stephen M Black

Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.

Circulation

Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, Sadagopan N, Hsu A, Costa MW, Gifford CA, van Bemmel JG, Hüttenhain R, Vedantham V, Conklin BR, Black BL, Bruneau BG, Steinmetz L, Krogan NJ, Pollard KS, Srivastava D

Transient Cell Cycle Induction in Cardiomyocytes to Treat Subacute Ischemic Heart Failure.

Circulation

Abouleisa RRE, Salama ABM, Ou Q, Tang XL, Solanki M, Guo Y, Nong Y, McNally L, Lorkiewicz PK, Kassem KM, Ahern BM, Choudhary K, Thomas R, Huang Y, Juhardeen HR, Siddique A, Ifthikar Z, Hammad SK, El-Baz AS, Ivey KN, Conklin DJ, Satin J, Hill BG, Srivastava D, Bolli R, Mohamed TMA

Abstract 9929: Inhibition of Receptor for Advanced Glycation End Products (RAGE) Reduces E-Cigarette-Induced Increase in Endothelial Permeability.

Circulation

Daniel D Han, Fengyun Xu, Ronak Derakhshandeh, Abel Huang, Adam Whitlatch, Rachel J Keith, Naomi Hamburg, Peter Ganz, Judith Hellman, Suzaynn Schick, Matthew L Springer, Leila Mohammadi

Abstract 11496: Increased Pulmonary Microvascular Endothelial Permeability by E-Cigarette Aerosol: The Pathway from Lung to Peripheral Blood Vessels.

Circulation

Leila Mohammadi, Daniel D Han, Xiaohui Fang, Fengyun Xu, Ronak Derakhshandeh, Judith Hellman, Jeffrey Gotts, Matthew L Springer

Abstract 11332: Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes.

Circulation

Barbara Gonzalez Teran, Maureen Pittman, Reuben Thomas, Franco Felix, Desmond Richmond-Buccola, Krishna Choudhary, Elisabetta Moroni, Colombo Giorgio, Arun Padmanabhan, Mauro Costa, Yu Huang, Michael Alexanian, Clara Lee, Bonie Cole, Kaitlen Samse-Knapp, Michael McGregor, Casey Gifford, Ruth Huttenhain, Bruce Gelb, Bruce Conklin, Brian L Black, Benoit Bruneau, Nevan Krogan, Katherine Pollard, Deepak Srivastava

Adrenergic-Thyroid Hormone Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity.

Circulation

Payumo AY, Chen X, Hirose K, Chen X, Hoang A, Khyeam S, Yu H, Wang J, Chen Q, Powers N, Chen L, Bigley RB, Lovas J, Hu G, Huang GN

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