The Journal of Immunology

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.

The Journal of Immunology

Levi Rupp, Kathrin Schumann, Kole T Roybal, Alexander Marson, Wendell A Lim

Role of the transcription factor Ikaros in development of autoimmune disease.

The Journal of Immunology

Hilde Schjerven, Seth Frietze, Si-Han Hai, Michelle Hermiston, Scott Kogan, Markus Muschen

Analysis of Ikaros tumor suppressor function in BCR-ABL1+ pre-B ALL reveals conserved target genes and biological pathways.

The Journal of Immunology

Hilde Schjerven, Etapong Fonabei Ayongaba, Jami McLaughlin, Donghui Cheng, Linn Margrethe Eggesbø, Ida Lindeman, Eugene Park, Owen N Witte, Stephen T Smale, Seth Frietze, Markus Muschen

STAT5 antagonism of B cell superenhancer networks initiates progenitor B cell leukemia and predicts patient survival (HEM1P.222).

The Journal of Immunology

Michael Farrar, Casey Katerndahl, Lynn Heltemes Harris, Mark Willette, christine Henzler, Rendong Yang, Kevin Silverstein, Seth Frietze, Hilde Schjerven, Laura Ramsey, Gregory Hubbard, Markus Muschen, Steven Kornblau

Ikaros tumor suppressor function in pre-B ALL: potential role of Ikaros target gene Ctnnd1 (IRM10P.621).

The Journal of Immunology

Hilde Schjerven, Linn Eggesbo, Ida Lindeman, Markus Muschen

Neutrophil recruitment into premalignant lesions differentially influences tumor growth versus progression. (TUM4P.928).

The Journal of Immunology

Adam Blaisdell, Takiko Daikoku, Chin Siean Tay, Sudhansu Dey, Adrian Erlebacher

Selective requirement of Ikaros zinc fingers in Treg and Th17 fate decision. (P1137).

The Journal of Immunology

Jennifer Heller, Hilde Schjerven, Ju Qiu, Aileen Lee, Stephen Smale, Liang Zhou

Role of Ikaros in hematopoiesis and tumor suppression: Selective functions of individual zinc fingers within the DNA-binding domain of Ikaros. (42.3).

The Journal of Immunology

Hilde Schjerven, Seth Frietze, Jami McLaughlin, Donghui Cheng, Peggy Farnham, Owen Witte, Stephen Smale

Stim1, PKCd and RasGRP proteins set a threshold for pro-apoptotic Erk signaling during B cell development (109.6).

The Journal of Immunology

Andre Limnander, Philippe Depeille, Tanya Freedman, Jen Liou, Michael Leitges, Tomohiro Kurosaki, Jeroen Roose, Arthur Weiss

Regulation of CD8 T cell responses by follicular dendritic cell-bound antigen (98.17).

The Journal of Immunology

Adrian Erlebacher, Maria Curotto de Lafaille, Juan Lafaille, Michael Carroll, Megan McCloskey

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