DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both.
The Developmental Biology Journal Club takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.
The Stem Cell Journal Club takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.
DSCB Journal Club Chair: Jeffrey Bush, PhD
2018-19 Schedule
The schedule for the 2018-19 academic year will be updated here shortly. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.
Friday, September 28, 2018 - 12:00-1:00 PM - Room: RMB Boardroom
Antara Rao (DSCB 2nd year student)
"Around the Brain in 80 Clusters: Single-Cell Analysis of the Aging Fly Brain"
Davie, K., Janssens, J., Koldere, D., De Waegeneer, M., Pech, U., Kreft, … Aerts, S. (2018). A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain. Cell.
Coaches: Todd Nystul and Alex Pollen
Sean de la O (DSCB 2nd year student)
"Endocrine cell type sorting and mature architecture in the islets of Langerhans require expression of Roundabout receptors in β cells"
Adams, M. Gilbert, J. Paiz, J. Bowman, F. Blum, B. Endocrine cell type sorting and mature architecture in the islets of Langerhans require expression of Roundabout receptors in β cells. Scientific Reports 8:10876, 1-12. (2018).
Coaches: Julie Sneddon and Sarah Knox
Wednesday, October 17, 2018 - 5:00-7:00 PM - Room: MH-1402
Matthew Schmitz (DSCB 2nd year student)
"It's Not All Ova."
Sozen, B. et al. Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures. Nature Cell Biology 20, 979-989. (2018).
Ryan Samuel (DSCB 2nd year student)
"Geometry Keeps Us In Shape: Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells"
Blin, G. et al. Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells. Development 145(18), 1-15. (2018).
Friday, October 26, 2018 - 12:00-1:00 PM - Room: RMB Boardroom
Nicole Koutsodendris (DSCB 2nd year student)
"APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types"
Lin, Y.T. et al. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types. Neuron 98(6), 1141-1154. (2018).
Coaches: Yadong Huang and Jorge Palop
Karishma Pratt (DSCB 2nd year student)
"Forget your New Year's Resolution to work out... Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model"
Choi, Se Hoon et al. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science 361(6406), 1-15. (2018).
Coaches: Daniel Lim and Georgia Panagiotakos
Wednesday, November 7, 2018 - 5:00-7:00 PM - Room: MH-2106
Emily Bulger (DSCB 1st year student)
"'The Only Constants in Life are Death and Taz(es)': The Hippo pathway effector Taz is required for cell morphogenesis and fertilization in zebrafish"
Dingare, C. et al. The Hippo pathway effector Taz is required for cell morphogenesis and fertilization in zebrafish. Development 10.1242/dev.167023. (2018).
Beatriz Alvarado (DSCB 2nd year student)
"We have to stick together!: Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation"
Rashid, M. et al. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development 144, 4002-4014. (2017).
Wednesday, November 28, 2018 - 5:00-7:00 PM - Room: MH-1402
Michael Mobaraki (DSCB 1st year student)
"One way the Oocyte resets: ‘A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis’"
Mak, W. et al. A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis. Cell Biosci 8(54):1-17. (2018).
Thi Nguyen (DSCB 1st year student)
"Science is Back-breaking Work!: Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis."
Zhang, X. et al. Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis. Nature Genetics. (2018).
Friday, December 7, 2018 - 12:00-1:00 PM - Room: RMB Boardroom
Matthew Schmitz (DSCB 2nd year student)
"Beauty is only skin deep: An elegant mechanism of epidermal homeostasis."
Mesa, K.R. et al. Homeostatic epidermal stem cell self-renewal is driven by local differentiation. Cell Stem Cell 23, 677-686. (2018).
Coaches: David Raleigh and Jeffrey Bush
Wednesday, January 9, 2019 - 5:00-7:00 PM - Room: MH-1402
Jean Luke Campos (DSCB 1st year student)
"Cellular Origami: The Drosophila Blood-Brain Barrier Adapts to Cell Growth by Unfolding of Pre-Existing Septate Junctions"
Babatz, F., Naffin, E., and Klämbt, C. The Drosophila Blood-Brain Barrier Adapts to Cell Growth by Unfolding of Pre-existing Septate Junctions. Developmental Cell 47, 697-710.e3. (2018).
Elina Kostyanovskaya (DSCB 2nd year student)
"Murine Eggs and (progr)ham: an egg-celent in vitro recipe"
Hikabe, O. et al. Reconstitution in vitro of the entire cycle of the mouse female germ line. Nature. 299-303. (2016)
Friday, January 18, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Elina Kostyanovskaya (DSCB 2nd year student)
"Can you have it all? Finding Your Balance in a Competitive Niche: The Story of Academia (but also spermatogenic stem cell homeostasis)"
Kitadate, Y. et al. Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche. Cell Stem Cell. 24(1):79-92. (2018).
Coaches: Todd Nystul & Bjoern Schwer
Beatriz Alvarado (DSCB 2nd year student)
"Duck(t) out early with Foxp1: Foxp1 is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence"
Fu, N.Y. et al. Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence. Dev Cell 47, 629-644 e628. (2018).
Coaches: Sarah Knox & Bjoern Schwer
Wednesday, February 20, 2019 - 5:00-7:00 PM - Room: MH-1402
Nicole Koutsodendris (DSCB 2nd year student)
TBA
Brandon Chacon (DSCB 1st year student)
TBA
Wednesday, March 13, 2019 - 5:00-7:00 PM - Room: MH-1401
Matthew Keefe (DSCB 1st year student)
TBA
Gugene Kang (DSCB 1st year student)
TBA
Friday, March 22, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Emily Bulger (DSCB 1st year student)
TBA
Thi Nguyen (DSCB 1st year student)
TBA
Wednesday, April 10, 2019 - 5:00-7:00 PM - Room: TBA
Nicholas Elder (DSCB 1st year student)
TBA
Karishma Pratt (DSCB 2nd year student)
TBA
Friday, April 19, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Jean Luke Campos (DSCB 1st year student)
TBA
Michael Mobaraki (DSCB 1st year student)
TBA
Wednesday, May 8, 2019 - 5:00-7:00 PM - Room: TBA
Antara Rao (DSCB 2nd year student)
TBA
Claire Maesner (DSCB 2nd year student)
TBA
Friday, May 17, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Matthew Keefe (DSCB 1st year student)
TBA
Brandon Chacon (DSCB 1st year student)
TBA
Wednesday, May 29, 2019 - 5:00-7:00 PM - Room: TBA
Zhiling Zhao (DSCB 2nd year student)
TBA
Sean de la O (DSCB 2nd year student)
TBA
Friday, June 7, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Nicholas Elder (DSCB 1st year student)
TBA
Gugene Kang (DSCB 1st year student)
TBA
Friday, June 14, 2019 - 12:00-1:00 PM - Room: RMB Boardroom
Ryan Samuel (DSCB 2nd year student)
"How An ALS Patient 'Chipped In' To Research: Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons."
Osaki, T., Uzel, S. G. M., and Kamm, R. D.Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons. Sci Adv 4:eaat5847. (2018).
Coaches: Daniel Lim and Georgia Panagiotakos
Zhiling Zhao (DSCB 2nd year student)
"Moving forward? Choose rear-wheel drive, like chemotaxis!"
Shellard, A., Szabó, A., Trepat, X. and Mayor, R. Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis. Science 362, 339–343. (2018).
Coaches: Takashi Mikawa and Orion Weiner