DSCB 216 Journal Clubs

DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.

The Wednesday Journal Club (formerly Developmental Biology) takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.

The Friday Journal Club (formerly Stem Cell) takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.

DSCB Journal Club Chair: Dan Wagner, PhD


Beginning 10/17/2021, Friday Journal Club will be held in-person on the Parnassus campus in N-729. Zoom will continue to be an option for those with medical restrictions.

  • 75 person capacity will be enforced
  • Physical distancing and masking is required at all times
  • Food is not allowed inside the classroom
Please review our Zoom etiquette guidelines before joining the meeting.

The Zoom link and meeting password will be sent out to those on the DSCB listservs the day of every journal club. Please contact Demian Sainz if you are not already on one of our listservs.

The Zoom meetings will be recorded and uploaded to the DSCB intranet. MyAccess sign-in is required in order to view anything on the DSCB Intranet.

2022-23 Schedule

Friday, October 21, 2022 - 12pm - Room: N-217

Miguel Turrero García, PhD (postdoc- Harwell lab)
"Should one ever be where one does not belong?"
Revah, O., Gore, F., Kelley, K.W. et al. Maturation and circuit integration of transplanted human cortical organoids. Nature 610, 319–326 (2022). https://doi.org/10.1038/s41586-022-05277-w

Jaz Harris (student)
"Transforming glia into neurons cures epilepsy?"
Lentini, Célia, et al. "Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy." Cell stem cell 28.12 (2021): 2104-2121.
Coaches: Dan Lim, MD, PhD & Arturo Alvarez-Buylla, PhD

Friday, January 20, 2023 - 12pm - Room: N-217

Lina Afonso (student)
"Getting Our Guts in Order"
Hamnett, Ryan, et al. “Regional Cytoarchitecture of the Adult and Developing Mouse Enteric Nervous System.” Current Biology, vol. 32, no. 20, Oct. 2022, pp. 4483-4492.e5, doi:10.1016/j.cub.2022.08.030.
Coaches: Faranak Fattahi, PhD & Georgia Panagiotakos, PhD

Aunoy Poddar (student)
"Cortical columns and Protocadherin patterns: Testing lineage-dependent organization"
Lv, X., Li, S., Li, J. et al. Patterned cPCDH expression regulates the fine organization of the neocortex. Nature 612, 503–511 (2022). https://doi.org/10.1038/s41586-022-05495-2
Coaches: Daniele Canzio, PhD & Cathryn Cadwell, MD, PhD

Friday, February 17, 2023 - 12pm - Room: N-217

Adriana Guajardo (student)
"Insights of skeletal integration during Axolotl limb regeneration" 
Camilo Riquelme-GuzmánStephanie L TsaiKaren Carreon PazCongtin NguyenDavid OriolaMaritta SchuezJan BruguésJoshua D CurrieTatiana Sandoval-Guzmán (2022) Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration eLife 11:e79966.

Coaches: Guo Huang, PhD & Ralph Marcucio, PhD

Vasileios Papakis (student)
"Modelling aging in a dish: bypassing reprogramming-associated cellular rejuvenation to better study Huntington's disease" 
Oh, Y.M., Lee, S.W., Kim, W.K. et al. Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy. Nat Neurosci 25, 1420–1433 (2022). https://doi.org/10.1038/s41593-022-01185-4
Coaches: Saul Villeda, PhD & Bruce Conklin, MD

Wednesday, March 8, 2023 - 5pm-7pm - Room: MH-1407

Emma Horton (student)
Research in Progress

Lina Afonso (student)
"hPSC-Derived Sacral Neural Crest Enables Rescue in a Severe Model of Hirschsprung’s Disease"
Fan, Yujie, et al. “hPSC-Derived Sacral Neural Crest Enables Rescue in a Severe Model of Hirschsprung’s Disease.” Cell Stem Cell, vol. 30, no. 3, Mar. 2023, pp. 264-282.e9, doi:10.1016/j.stem.2023.02.003

Friday, March 17, 2023 - 12pm - Room: N-217

Rose Zhou (student)
"Uncovering the Role of Microglia in Myelin Health Maintenance"
McNamara, N.B., Munro, D.A.D., Bestard-Cuche, N. et al. Microglia regulate central nervous system myelin growth and integrity. Nature 613, 120–129 (2023). https://doi.org/10.1038/s41586-022-05534-y
Coaches: Stephen Fancy, PhD, DVM & Tomasz Nowakowski, PhD

Jonathan Ramirez (student)
"Rack-ing Up the Regeneration: Antler Stem Cells Reveal Un-deer-appreciated Potential"
Qin, T. et al. A population of stem cells with strong regenerative potential discovered in deer antlers. Science 379, 840–847 (2023)
Coaches: Andrew Yang, PhD & Faranak Fattahi, PhD

Friday, March 24, 2023 - 12pm - Room: N-217

Emma Horton (student)
"Cxcr4 and Cxcl12 cooperate to guide migration of caudal ganglionic eminence derived neurons"
Venkataramanappa, S. et al. Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. Cell Rep. 40, 111157 (2022)
Coaches: John Rubenstein, MD, PhD & Corey Harwell, PhD

Kevin Chen (student)
"Watching paint dry: Live-cell imaging of single nucleosomes and chromatin"
Live-cell imaging uncovers the relationship between histone acetylation, transcription initiation, and nucleosome mobility Matthew N. Saxton1 , Tatsuya Morisaki1 , Diego Krapf2 , Hiroshi Kimura3,4, and Timothy J. Stasevich1,3 Biorxiv, March 3, 2023
Coaches: Robert Blelloch, MD, PhD & Daniel Wagner, PhD

Friday, April 14, 2023 - 12pm - Room: HSW-303

David Wen (student)
"From bench to bytesize — CRISPR screens on a computer chip"
Kamimoto, K., Stringa, B., Hoffmann, C.M. et al. Dissecting cell identity via network inference and in silico gene perturbation. Nature 614, 742–751 (2023). https://doi.org/10.1038/s41586-022-05688-9
Coaches: Dan Wagner, PhD & Ryan Corces, PhD

Ricardo Espinosa Lima (student)
"Changing Geometry With Hox Genes: A Genetic and Physical Story"
Hox genes modulate physical forces to differentially shape small and large intestinal epithelia Hasreet K. Gill, Sifan Yin, Nandan L. Nerurkar, John C. Lawlor, Tyler R. Huycke, L. Mahadevan, Clifford J. Tabin bioRxiv 2023.03.15.532602; doi: https://doi.org/10.1101/2023.03.15.532602
Coaches: Jeremy Reiter, MD, PhD & Michael Kattah, MD, PhD

Wednesday, May 10, 2023 - 5pm-7pm - Room: MH-1407

David Wen (student)

Vasileios Papakis (student)

Wednesday, May 24, 2023 - 5pm-7pm - Room: MH-1407

Adriana Guajardo (student)
"The evolution of multicellularity through environmental adaptations"
Cornwallis, C.K., Svensson-Coelho, M., Lindh, M. et al. Single-cell adaptations shape evolutionary transitions to multicellularity in green algae. Nat Ecol Evol (2023). https://doi.org/10.1038/s41559-023-02044-6

Karissa Hansen (student)
"Investigating the role of DNA loop extrusion in transcriptional regulation"
Nora Lab