DSCB 216 Journal Clubs

DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.


The Wednesday Journal Club (formerly Developmental Biology) takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.


The Friday Journal Club (formerly Stem Cell) takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.


DSCB Journal Club Chair: Jeffrey Bush, PhD


**COVID-19 UPDATE**

All DSCB Journal Clubs will be conducted via Zoom meeting until further notice. You will also be able to ask questions of the presenters via Zoom. Please review our Zoom etiquette guidelines before joining the meeting.


The Zoom link and meeting password will be sent out to those on the DSCB listservs the day of every journal club. Please contact Demian Sainz if you are not already on one of our listservs.


The Zoom meetings will be recorded and uploaded to the DSCB intranet. MyAccess sign-in is required in order to view anything on the DSCB Intranet.

2020-21 Schedule

The schedule for the 2020-21 academic year will be updated here shortly. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.

Friday, November 13, 2020 - 12:00pm - 1:00pm - Room: Zoom

Elliott Sherr (faculty)
“3D excitement!!”
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome:  
Khan, T.A., Revah, O., Gordon, A. et al. Neuronal defects in a human cellular model of 22q11.2 deletion syndrome. Nat Med (2020). https://doi.org/10.1038/s41591-020-1043-9

Karissa Hansen (student)
"Disentangling Polycomb-mediated transcriptional repression."
Dobrinić P, Szczurek AT, and Klose RJ. PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency. bioRxiv 2020. doi: https://doi.org/10.1101/2020.10.09.333294 
Coaches: Barbara Panning and Robert Blelloch


Friday, January 15, 2021 - 12:00pm - 1:00pm - Room: Zoom

Licia Selleri (faculty)
"'EnSERT' variant alleles of the Shh limb enhancer to grow additional digits"
Kvon EZ, et al. Comprehensive In Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants. Cell. 2020 Mar 19;180(6):1262-1271.e15. doi: 10.1016/j.cell.2020.02.031. Epub 2020 Mar 12. PMID: 32169219; PMCID: PMC7179509.

Eliza Gaylord (student)
"Taming the Teratoma: Defining the Teratoma as a Model for Multi-lineage Human Development"
McDonald D, Wu Y, Dailamy A, Tat J, Parekh U, Zhao D, Hu M, Tipps A, Zhang K, Mali P. Defining the Teratoma as a Model for Multi-lineage Human Development. Cell (2020). https://doi.org/10.1016/j.cell.2020.10.018 
Coaches: Julie Sneddon and Robert Blelloch


Friday, April 16, 2021 - 12:00pm - 1:00pm - Room: Zoom

Ali Kalantari (student)
"Having a blast with stem cells: blastocyst-like structures made from hPSCs"
Yu, L., Wei, Y., Duan, J. et al. Blastocyst-like structures generated from human pluripotent stem cells. Nature 591, 620–626 (2021). https://doi.org/10.1038/s41586-021-03356-y
Coaches: Barbara Panning and Aaron Tward 

Bonnie Zhu (student)
"Gpr161 ciliary pools prevent hedgehog pathway hyperactivation phenotypes specifically from lack of Gli transcriptional repression."
Sun-Hee Hwang, Bandarigoda N. Somatilaka, Kevin White, Saikat Mukhopadhyay. Gpr161 ciliary pools prevent hedgehog pathway hyperactivation phenotypes specifically from lack of Gli transcriptional repression. bioRxiv 2021. doi: https://doi.org/10.1101/2021.01.07.425654
Coaches: Thomas Nowakowski and Jeremy Reiter


Friday, May 14, 2021 - 12:00pm - 1:00pm - Room: Zoom

Haley Smith (student)
"Shapeshifting from an oval to a cup: mouse epiblast morphogenesis"
Weberling A, Zernicka-Goetz M. Trophectoderm mechanics direct epiblast shape upon embryo implantation. Cell Rep. 2021 Jan 19;34(3):108655. doi: 10.1016/j.celrep.2020.108655. PMID: 33472064; PMCID: PMC7816124.
Coaches: Daniel Wagner and Robert Blelloch

Irena Roy (student)
"Defying Waddington's landscape: in vivo reprogramming of cranial neural crest"
Zalc A, Sinha R, Gunsagar G, Wesche D, Daszczuk P, Swigot T, Weissman I, Wysocka J, et al. Reactivation of the pluripotency program precedes formation of the cranial neural crest. Science 2021; 371(6529). doi: 20.1126/science.abb4776
Coaches: Faranak Fattahi and Licia Selleri


Friday, June 4, 2021 - 12:00pm - 1:00pm - Room: Zoom

Emily Wolfgram (student)
"Regulation of oogenesis by the myoepithelium in the Drosophila ovary"
Weaver LN, Drummond-Barbosa D. Hormone receptor 4 is required in muscles and distinct ovarian cell types to regulate specific steps of Drosophila oogenesis. Development. 2021 Mar 9;148(5):dev198663. doi: 10.1242/dev.198663. PMID: 33547134; PMCID: PMC7970067.
Coaches: Todd Nystul and Diana Laird