DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both. See the DSCB Journal Club Archives in the right sidebar for past years' journal clubs.
The Developmental Biology Journal Club takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.
The Stem Cell Journal Club takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.
DSCB Journal Club Chair: Jeffrey Bush, PhD
2019-20 Schedule
Friday, September 27, 2019 - 12:00pm - 1:30pm - Room: N-721
Todd Nystul (faculty)
"Know thy surroundings: factors that shape keratinocyte progenitor cell fate"
Box, K., Joyce, B.W., and Devenport, D. (2019). Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis. Elife 8.
Nicholas Elder (student)
"Putting in the Legwork: An Organoid Model of the Developing Limb Bud."
Mori, S. et al. Self-organized formation of developing appendages from murine pluripotent stem cells. Nat. Commun. 10, 3802 (2019)
Coaches: Alex Pollen and Tien Peng
Wednesday, October 9, 2019 - 5:00pm - 7:00pm - Room: MH-1407
Emily Bulger (student)
"Pesky Pescoids: How 'Self-organized symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation'"
Trivedi V, Fulton T, Attardi A, Anlas K, Dingare C, Martinez Arias A, Steventon BJ."Self-organized symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation" BioRxiv. 2019 Sept 14. DOI 10.1101/769257
Nicholas Elder (student)
"Shedding some light on signaling dynamics and cell fate in Drosophila"
Johnson, H. E., Shvartsman, S. Y. & Toettcher, J. E. Signaling dynamics control cell fate in the early Drosophila embryo. BioRxiv (2018). doi:10.1101/342998
Friday, October 18, 2019 - 12:00pm - 1:00pm - Room: N-721
Elphege Nora (faculty)
"A symmetric toggle switch explains the onset of random X inactivation in different mammals"
Mutzel et al., A symmetric toggle switch explains the onset of random X inactivation in different mammals. Nature Structural & Molecular Biology volume 26, pages350–360 (2019), doi:10.1038/s41594-019-0214-1
Brandon Chacon (student)
"When they go low, we go high"
Soldatov et al., Spatiotemporal structure of cell fate decisions in murine neural crest.Science 07 Jun 2019: Vol. 364, Issue 6444, eaas9536
Coaches: Faranak Fattahi and Alex Pollen
Wednesday, October 30, 2019 - 5:00pm - 7:00pm - Room: MH-1407
Eliza Gaylord (student)
"Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function."
Mullapudi, S. T., Boezio, G. L. M., Rossi, A., Marass, M., Matsuoka, R. L., Matsuda, H., Helker, C. S. M., Yang, Y. H. C. Stainier, D. Y. R. (2019). Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function. Development, dev.173674.
Brandon Chacon (student)
"Mouse prostates flying through the space-time continuum!"
Elisavet Tika, Marielle Ousset, Anne Dannau, Cédric Blanpain. Spatiotemporal regulation of multipotency during prostate development. Development 2019 146: dev180224 doi: 10.1242/dev.180224 Published 23 October 2019
Friday, November 15, 2019 - 12:00pm - 1:00pm - Room: N-721
Diane Barber (faculty)
"Form supports function: connecting actin dynamics to chromatin remodeling and cell fate reprogramming"
Hu, X., Liu, Z.Z., Chen, X. et al. MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation. Nat Commun 10, 1695 (2019)
Michael Mobaraki (student)
"Overtime Subtle Variability in Transcription and Methylation Arises in Mouse Muscle Stem Cells"
Hernando-Herraez et al., Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells, Nature Communications 2019 Sep 25; 10(1):4361.
Coaches: Robert Blelloch and Alex Pollen
Friday, January 17, 2020 - 12:00pm - 1:00pm - Room: N-721
Sophie Dumont (faculty)
"How mammalian oocytes build a spindle without centrosomes"
Science. 2019 Jun 28;364(6447).
A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes.
So C, Seres KB, Steyer AM, Mönnich E, Clift D, Pejkovska A, Möbius W, Schuh M
Matthew Keefe (student)
"Got Developing Spinal Cord Circuitry? Go Fish"
Wan, Y., Wei, Z., Looger, L.L., Koyama, M., Druckmann, S., and Keller, P.J. (2019). Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit. Cell 179, 355-372.e23.
Coaches: Georgia Panagiotakos and Faranak Fattahi
Wednesday, January 29, 2020 - 5:00pm - 7:00pm - Room: MH-1406
Reed McMullen (student)
"TBD"
Xin Zhu et al,. Cilia-driven asymmetric Hedgehog signalling determines the amphioxus left-right axis by controlling Dand5 expression. Development 2020 147: dev182469 doi: 10.1242/dev.182469 Published 13 January 2020
Michael Mobaraki (student)
"Profiling Protein Changes in Blood Plasma Overtime"
Benoit Lehallier et al,. Undulating changes in human plasma proteome profiles across the lifespan. Nature Medicine volume 25, pages1843–1850(2019).
Wednesday, February 12, 2020 - 5:00pm - 7:00pm - Room: MH-1406
Karissa Hansen (student)
TBD
Matthew Keefe (student)
TBD
Friday, February 21, 2020 - 12:00pm - 1:00pm - Room: N-721
TBD (faculty)
TBD
Jean Luke Campos (student)
TBD
Wednesday, March 4, 2020 - 5:00pm - 7:00pm - Room: MH-1406
Alexander Merriman (student)
TBD
Jean Luke Campos (student)
TBD
Friday, March 20, 2020 - 12:00pm - 1:00pm - Room: N-721
Thi Nguyen (student)
TBD
Emily Bulger (student)
TBD
Wednesday, April 1, 2020 - 5:00pm - 7:00pm - Room: MH-1406
Aris Taychameekiatchai (student)
TBD
Gugene Kang (student)
TBD
Friday, April 17, 2020 - 12:00pm - 1:00pm - Room: N-721
Gugene Kang (student)
TBD
Eliza Gaylord (student)
TBD
Wednesday, April 29, 2020 - 5:00pm-7:00pm - Room: MH-1406
Thi Nguyen
TBD
Friday, May 15, 2020 - 12:00pm - 1:00pm - Room: N-721
Alexander Merriman (student)
TBD
Reed McMullen (student)
TBD
Friday, June 5, 2020 - 12:00pm - 1:00pm - Room: N-721
Aris Taychameekiatchai (student)
TBD
Karissa Hansen (student)
TBD