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DSCB 216 Journal Clubs

DSCB journal clubs are held twice a month. First and second year DSCB students are required to present once in each of the two journal clubs. Students in their third year and beyond are encouraged to attend and participate in both.

The Developmental Biology Journal Club takes place at the Mission Bay campus. This series is student-led and is intended to be a less formal environment in which students can develop their presentation skills in a group of peers. Students in their second year and beyond are encouraged to serve as “student coaches” to help first year students prepare their presentations. Papers selected for presentation in this journal club should be recent and impactful manuscripts related to developmental biology.

The Stem Cell Journal Club takes place on the Parnassus campus, with two presenters each week. Student presenters are required to work with 2 faculty coaches and any number of student coaches (usually 2-3) to prepare for their presentations. Papers presented in this series should be recent and impactful manuscripts related to stem cell biology.

DSCB Journal Club Chair:  Jeffrey Bush, PhD

 

2015-16 Schedule

Friday, September 11, 2015
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Buddy White (2nd year student)
"Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease."
Hamilton L et al. 2015. Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease. Cell Stem Cell, In press. 27 August, ISSN 1934-5909. doi.org/10.1016/j.stem.2015.08.001.
Coaches: Yadong Huang and Georgia Panagiotakos

Andrew Brack
(faculty)
"Skeletal muscle regeneration and aging."
Rodgers T, et al. mTorc1 controls the adaptive transition of quiescent stem cells from G0 to G Alert. Nature. 2014. Jun 19; 510 (7505): 393-396. doi:10.1038/nature13255.
 

Wednesday, September 30, 2015
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Jake Freimer (5th year student)
Zanet J, et al. Pri sORF peptides induce selective proteasome-mediated protein processing. Science. 2015 Sep 18;349(6254):1356-8. doi: 10.1126/science.aac5677.
Student coaches: None


Friday, October 9, 2015
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Valerie Weaver (faculty)
"Forcing Stemness."
Guo J, et al. Actin stress in cell reprogramming. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5252-61. doi: 10.1073/pnas.1411683111.

Ashley Libby (2nd year student)
"Suck it Up: Endocytosis and Embryonic Wound Repair."
Hunter MV, et al. Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair. J Cell Biol. 2015 Aug 31;210(5):801-16. doi: 10.1083/jcb.201501076.
Coaches: Bruce Conklin and Nancy Boudreau


Wednesday, October 28, 2015
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Hanna Kirby (2nd year student)
Potts K, et al. Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL. Blood. 2015 Aug 6;126(6):807-16. doi:10.1182/blood-2014-12-616607.

Ying Yang (Postdoc)
Pardo-Saganta A, et al. Parent stem cells can serve as niches for the daughter cells. Nature. 2015 Jul 30;523(7562):597-601: 10.1038/nature14553.

Friday, November 13, 2015
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Akela Kuwahara (2nd year student)
"Collaborative repair of DNA damage between between male and female germ lines."
Lord, T. & Aitken, R. J. Fertilization stimulates 8-hydroxy-2′-deoxyguanosine repair and antioxidant activity to prevent mutagenesis in the embryo. Dev. Biol. 406, 1–13 (2015).
Coaches: Canan Doganli and Paolo Rinaudo

Todd Nystul (faculty)
"Turning eukaryotic evolution inside out."
Baum DA & Baum B. An inside-out origin for the eukaryotic cell. BMC Biol. 2014 Oct 28;12:76. doi: 10.1186/s12915-014-0076-2.


Wednesday, November 18, 2015
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Lauren Byrnes (1st year student)
Jacob Kimmel (1st year student)


Wednesday, December 9, 2015
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Melissa Truong (1st year student)
"Let me go!: An E- to N-cadherin switch controls contact inhibition of locomotion in neural crest cells."
Scarpa E, et al. Cadherin switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces. Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012.
Coach: Ashley Libby

Buddy White (2nd year student)
"The Neuron Nursery"
Sultan S, et al. Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes. Neuron. 2015 Nov 18. pii: S0896-6273(15)00931-9. doi: 10.1016/j.neuron.2015.10.037.
Coach: Liz Wheatley


Friday, January 15, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Daniel He (2nd year student)
“Flabby chromatin is bad for muscle stem cell maintenance.”
Boonsanay V, et al. Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation. Cell Stem Cell. 2015 Dec 5. pii: S1934-5909(15)00500-7. doi: 10.1016/j.stem.2015.11.002.
Coaches: Daniel Lim and Andrew Brack

Diane Barber (faculty)
"pHascintating pHindings on pH and stem cell behaviors."
Research talk


Wednesday, January 27, 2016
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall S-261, Mission Bay
Steven Cincotta (1st year student)
"Hissssstones, Enhancersssss, and Divergence of cisssss-Regulatory Element Function During Snake Evolution." 
Infante C, et al. Shared Enhancer Activity in the Limbs and Phallus and Functional Divergence of a Limb-Genital cis-Regulatory Element in Snakes. Dev Cell. 2015 Oct 12;35(1):107-19. doi: 10.1016/j.devcel.2015.09.003. Epub 2015 Oct 1.
Coach: Bonnie Cole

Ashely Libby (2nd year student)
"Are you afraid of the dark? Optogenetic manipulation of morphogenesis."
Guglielmi G, et al. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell 35, no. 5 (July 12, 2015): 646–60. doi:10.1016/j.devcel.2015.10.020.
Coaches: Hanna Kirby and Sara Taylor

Friday, February 12, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Bonnie Cole (2nd year student)
"Ready. Set. Go! A quantitative look into the mechanism of how stem cells choose between epiblast vs. primitive endoderm cell fates."
Schröter C, et al. FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells. Development. 2015 Dec 15;142(24):4205-16. doi: 10.1242/dev.127530.
Coaches: Todd Nystul and Robert Blelloch

Melissa Truong (1st year student)
"FOXO gets the blood pumping: FOXO1 couples metabolic activity and growth state in the vascular endothelium."
Wilhelm K, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016 Jan 14;529(7585):216-20. doi: 10.1038/nature16498.
Coaches: Rong Wang and Matt Springer


Wednesday, February 24, 2016
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Nate Meyer (1st year student)
Bonnie Cole (2nd year student)


Friday, March 4, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, Nursing, N-721, Parnassus
Hanna Kirby (2nd year student)
Sarah Knox (faculty)

Friday, March 11, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Nathaniel Meyer (1st year student)
Jacob Kimmel (1st year student)


Wednesday, March 30, 2016
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Sung Hong (1st year student)
Daniel He (2nd year student)

Friday, April 8, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Sung Jun Hong (1st year student)
Steven Cincotta (1st year student)


Wednesday, April 27, 2016
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
Arpana Arjun (1st year student)
Akela Kuwahara (2nd year student)

Friday, May 13, 2016
Stem Cell Journal Club
12:00 p.m. - 1:00 p.m, RMB Boardroom, RMB-1041, Parnassus
Lauren Byrnes (1st year student)
Arpana Arjun (1st year student)


Wednesday, May 25, 2016
Developmental Biology Journal Club
5:30-6:30 p.m.  Genentech Hall N-114, Mission Bay
TBD

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2013-14 Archive
2012-13 Archive
2011-12 Archive