Nature communications

Ultra-deep sequencing validates safety of CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells.

Nature communications

Cromer MK, Barsan VV, Jaeger E, Wang M, Hampton JP, Chen F, Kennedy D, Xiao J, Khrebtukova I, Granat A, Truong T, Porteus MH

Targeting transcription in heart failure via CDK7/12/13 inhibition.

Nature communications

Hsu A, Duan Q, Day DS, Luo X, McMahon S, Huang Y, Feldman ZB, Jiang Z, Zhang T, Liang Y, Alexanian M, Padmanabhan A, Brown JD, Lin CY, Gray NS, Young RA, Bruneau BG, Haldar SM

G1/S restriction point coordinates phasic gene expression and cell differentiation.

Nature communications

DeVeale B, Liu L, Boileau R, Swindlehurst-Chan J, Marsh B, Freimer JW, Abate A, Blelloch R

Metabolic control of progenitor cell propagation during Drosophila tracheal remodeling.

Nature communications

Li Y, Dong P, Yang Y, Guo T, Zhao Q, Miao D, Li H, Lu T, Xia F, Lyu J, Ma J, Kornberg TB, Zhang Q, Huang H

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.

Nature communications

Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD

Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation.

Nature communications

Kreimer A, Ashuach T, Inoue F, Khodaverdian A, Deng C, Yosef N, Ahituv N

Deep phenotyping of Alzheimer's disease leveraging electronic medical records identifies sex-specific clinical associations.

Nature communications

Tang AS, Oskotsky T, Havaldar S, Mantyh WG, Bicak M, Solsberg CW, Woldemariam S, Zeng B, Hu Z, Oskotsky B, Dubal D, Allen IE, Glicksberg BS, Sirota M

Unprotected peptide macrocyclization and stapling via a fluorine-thiol displacement reaction.

Nature communications

Islam MS, Junod SL, Zhang S, Buuh ZY, Guan Y, Zhao M, Kaneria KH, Kafley P, Cohen C, Maloney R, Lyu Z, Voelz VA, Yang W, Wang RE

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states.

Nature communications

Song H, Weinstein HNW, Allegakoen P, Wadsworth MH, Xie J, Yang H, Castro EA, Lu KL, Stohr BA, Feng FY, Carroll PR, Wang B, Cooperberg MR, Shalek AK, Huang FW

Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation.

Nature communications

Yang Y, Paivinen P, Xie C, Krup AL, Makela TP, Mostov KE, Reiter JF

Pages