Science (New York, N.Y.)

Vertebrate diapause preserves organisms long term through Polycomb complex members.

Science (New York, N.Y.)

Hu CK, Wang W, Brind'Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.

Science (New York, N.Y.)

Kondo Y, Ognjenovic J, Banerjee S, Karandur D, Merk A, Kulhanek K, Wong K, Roose JP, Subramaniam S, Kuriyan J

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism.

Science (New York, N.Y.)

Maini Rekdal V, Bess EN, Bisanz JE, Turnbaugh PJ, Balskus EP

Oligogenic inheritance of a human heart disease involving a genetic modifier.

Science (New York, N.Y.)

Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D

Single-cell genomics identifies cell type-specific molecular changes in autism.

Science (New York, N.Y.)

Velmeshev D, Schirmer L, Jung D, Haeussler M, Perez Y, Mayer S, Bhaduri A, Goyal N, Rowitch DH, Kriegstein AR

Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.

Science (New York, N.Y.)

Wienert B, Wyman SK, Richardson CD, Yeh CD, Akcakaya P, Porritt MJ, Morlock M, Vu JT, Kazane KR, Watry HL, Judge LM, Conklin BR, Maresca M, Corn JE

Immunity as a continuum of archetypes.

Science (New York, N.Y.)

Mujal AM, Krummel MF

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.

Science (New York, N.Y.)

Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, Field KA, Reeder DM, Maden M, Yartsev MM, Wolfgang MJ, Grützner F, Scanlan TS, Szweda LI, Buffenstein R, Hu G, Flamant F, Olgin JE, Huang GN

Glutamate signaling at cytoneme synapses.

Science (New York, N.Y.)

Huang H, Liu S, Kornberg TB

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