DSCB Journal Clubs Archive 2016-17

Friday, September 23, 2016

Stem Cell Journal Club

Andy Chang, PhD (faculty)
"An adult neural stem cell population with therapeutic potential for Parkinson's disease"
Navarro-Guerrero, E et.al. "Gene Expression Profiling Supports the Neural Crest Origin of Adult Rodent Carotid Body Stem Cells and Identifies CD10 as a Marker for Mesectoderm-Committed Progenitors." Stem Cells. 2016 Jun; 34(6):1637-50.

Sung Jun Hong (2nd year student)
"Polycomb repressive complex 2 (PCR2) silences genes responsible for neurodegeneration"
von Schimmelmann, et al. "Polycomb repressive complex 2 (PCR2) silences genes responsible for neurodegeneration." Nature Neuroscience. 2016 August (advance online pub). 
Coaches: Daniel Lim and Georgia Panagiotakos  

Wednesday, September 28, 2016

Developmental Biology Journal Club

Melissa Truong (2nd year student)
"Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization"
Zhou, Qinghua, et al. "Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization." Science. 2016 Jul 22; 353(6297): 394-9. 
Student Coach: Akela Kuwahara

Jacob Kimmel (2nd year student)
"Fascin regulates nuclear movement and deformation in migrating cells"
Jayo et al. "Fascin regulates nuclear movement and deformation in migrating cells." Dev Cell.2016. Aug 222; 38(4): 371-83.

Friday, October 21, 2016

Stem Cell Journal Club

Todd Nystul (faculty)
"Multi-organ Mapping of Cancer Risk"
Zhu, L et al. "Multi-organ Mapping of Cancer Risk." Cell. 2016. 166(5): 1132-1146.

Steven Cincotta (2nd year student)
"The Role of 3D Genome Architecture in Somatic Cell Reprogramming"
Beagan JA, et al."Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming." Cell Stem Cell. 2016. May 5; 18(5):611-24.
Coaches: Todd Nystul and Wallace Marshall

Wednesday, November 16, 2016

Developmental Biology Journal Club

Arpana Arjun (2nd year student)
"Chd8 tunes neural progenitor and differentiation during embryonic neurogenesis"
Durak, O et al. "Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling." Nature Neuroscience. 2016. 19: 1477-1488.

Steven Cincotta (2nd year student)
"Episode II: Return of the Snake Enhancerssss"
Kvon, Evgeny Z. et al. "Progressive Loss of Function in a Limb Enhancer during Snake Evolution." Cell. 2016. 167 (3):633-642.

Friday, January 20, 2017

Stem Cell Journal Club

Marco Conti (faculty)
"Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations"
Kang, E., et al. "Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations." Nature. 2016. 540: 270-275.

Arpana Arjun (2nd year student)
"Identification of a population of neural progenitor cells located in the meninges"
Bifari, F., et al. "Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex.” Cell Stem Cell. 2016. 20:1-14.
Coaches: Georgia Panagiotakos and Barbara Panning

Wednesday, January 25, 2017

Developmental Biology Journal Club

Bryan Marsh (1st year student)
"Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development"
Anderson K.M., et al. “Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development.” Nature. 2016. 539(7629):433-436.

Lauren Byrnes (2nd year student)
"Axolotl Limb Regeneration Requires Neuregulin-1 Signaling"
Farkas, J.E., et al. "Neuregulin-1 signaling is essential for nerve-dependent axolotl limb regeneration." Development. 2016. 143: 2724-2731. 
 

Friday, February 17, 2017

Stem Cell Journal Club

Nadav Ahituv (faculty)
"The seahorse genome and the evolution of its specialized morphology"
Lin, Q., et al. "The seahorse genome and the evolution of its specialized morphology." Nature. 2016. 540: 395-399.

Jacob Kimmel (2nd year student)
"Switching states: Inference of stem cell state transitions from end-point measurements"
Hormoz, S., et. al. "Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements." Cell Systems. 2016.  3 (5): 419-433.
Coaches: Susan Fisher and Wallace Marshall 

Wednesday, February 22, 2017

Developmental Biology Journal Club

Jessica Xie (1st year student)
Li, Y., et al. "Induction of Expansion and Folding in Human Cerebral Organoids." Cell Stem Cell. 2017. 20:1-12.

Nathaniel Meyer (2nd year student)
"The Plasticity of Pericytes: A Premature Promise?"
Guinmaraes-Camboa, N., et al. “Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.” Cell Stem Cell. 2016. 20: 1-15.

 

Friday, March 17, 2017

Stem Cell Journal Club

Tien Peng (faculty)
"In vivo cellular reprogramming: elixir of youth with a side of teratoma"
Ocampo, A., et al. "In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming." Cell. 2016. 167(7): 1719-1733.

Melissa Truong (2nd year student)
"Tissue damage and senescence provide critical signals for cellular reprogramming in vivo"
Mosteiro, L., et al. "Tissue damage and senescence provide critical signals for cellular reprogramming in vivo." Science. 2016. 354(6315): 1020-1032.
Coaches: Andrew Brack and Barbara Panning

Wednesday, March 29, 2017

Developmental Biology Journal Club

Ryan Boileau (1st year student)
"Organizing the organizers of organs: Maternal FoxH1 in mesendoderm development"
Charney, R., et al. “Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program.” Developmental Cell. 2017. 40: 1-13.

Friday, April 21, 2017

Stem Cell Journal Club


Ryan Boileau (1st year student)
"In pursuit of totipotency: extending the developmental potential of cultured ESCs"
Yang, Y., et al. "Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency." Cell. 2017.  169(2): 243-257.
Coaches: Miguel Ramalho-Santos and TBA

Wednesday, April 26, 2017

Developmental Biology Journal Club

Lila Nearhing (1st year student)
“A Role for Macrophages in Tissue Remodeling”
Eom, D.S. and D.M. Parichy. "A macrophage relay for long-distance signaling during postembryonic tissue remodeling." Science. 2017. 355:1317-1320.​ 

Sung Hong (2nd year student)
"Deletion of psychiatric risk gene Cacna1 impairs hippocampal neurogenesis in cell-autonomous fashion"
Volkening, B., et al. “Deletion of psychiatric risk gene Cacna1 impairs hippocampal neurogenesis in cell-autonomous fashion.” Gila. 2017. 65(5): 817-827.

Friday, May 19, 2017

Stem Cell Journal Club

Andrew Brack (faculty)
"A Twist2-dependent progenitor cell contributes to adult skeletal muscle"
Liu, N., et al. "A Twist2-dependent progenitor cell contributes to adult skeletal muscle." Nature Cell Biology. 2017 19(3): 202-213.​

Lila Neahring (1st year student)
"Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal"
Yan, K.S., et al. "Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal." Nature. 2017. doi:10.1038/nature22313.
Coaches: Todd Nystul and Ophir Klein

Friday, June 9, 2017

Stem Cell Journal Club

Jessica Xie (1st year student)
"A meeting of worlds: connecting different brain regions in a dish"
Birey, F., et al.  "Assembly of functionally integrated human forebrain spheroids." 2017. Nature 545: 54-59.
Coaches: Alex Pollen and Eric Huang

Bryan Marsh (1st year student)
"Non-traditional modes of stem cell replacement: Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine"
Minoux, M., et al. "Gene bivalency at Polycomb domains regulates cranial neural crest positional identity." 2017. Science 355(6332): eaal2913.
Coaches: Todd Nystul and Guo Huang