DSCB Journal Clubs Archive 2012-13

September 2012
Tue, 9/11/12 Noon – Parnassus room HSW 300
Stem Cell Journal Club
Presenter: Matt Donne
Rock Lab
Title: Put a RING On It: The Role of Ubiquitin Ligases in Intestinal Stem Cell Regulation
Paper: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. 
Koo BK, Spit M, Jordens I, Low TY, Stange DE, van de Wetering M, van Es JH, Mohammed S,
Heck AJ, Maurice MM, Clevers H. Nature. 2012 Aug 15. doi: 10.1038/nature11308.

Wed, 9/19/12 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Justin Ellis
Rowitch Lab
Title: The Better to See You With
Paper: Self-Formation of Optic Cups and Storable Stratified Neural Retina from Suman ESCs.
Tokushige Nakano, Satoshi Ando, Nozomu Takata, Masako Kawada, Keiko Muguruma, Kiyotoshi Sekiguchi, Koichi Saito,  Shigenobu Yonemura, Mototsugu Eiraku, and Yoshiki Sasai.  Cell Stem Cell 10, 771-785, June 14, 2012.

October 2012
Wed, 10/3/12 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Jake Freimer
Paper: TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication. Svetlana Petruk, Yurii Sedkov, Danika M. Johnston, Jacob W. Hodgson, Kathryn L. Black, Sina K. Kovermann, Samantha Beck,  Eli Canaani, Hugh W. Brock, and Alexander Mazo. Cell 150, 1-12, August 31, 2012

Tue, 10/9/12 Noon – Parnassus HSW 300
Stem Cell Journal Club
Presenter: Christina Theodoris
Srivastava Lab
Paper: Clonally dominant cardiomyocytes direct heart morphogenesis. Vikas Gupta & Kenneth Poss. Nature Vol 484, 479-485, April 26, 2012.

Wed, 10/17/12 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Kate Woronowicz
Schneider Lab
Paper: SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice. Satoru Sasagawa1, Hiroshi Takemori, Tatsuya Uebi, Daisuke Ikegami, Kunihiko Hiramatsu, Shiro Ikegawa, Hideki Yoshikawa and Noriyuki Tsumaki. Development 139, 1153-1163 January 5, 2012.

November 2012
Wed, 11/7/12 5:30 p.m. Mission Bay CVRI SC341
Developmental Biology Journal Club
Presenter: Christinia Theodoris
Srivastava Lab
Paper: Predictive computation of genomic logic processing functions in embryonic development.  Proceedings of the National Academy of Sciences Vol 109, no. 41 16434-16442. 

Tue, 11/13/12 Noon – Parnassus room HSW 300
Stem Cell Journal Club
Presenter: Amanda Mason
Finkbeiner Lab
Title: An Old Drug with New Tricks: Metformin Promotes Neurogenesis and Enhances Spatial
Memory Formation
Paper: Wang et al, 2012. Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation.  Cell Stem Cell 11:23-35

Wed, 11/21/12 5:30 p.m. Mission Bay CVRI SC159-CANCELLED
Developmental Biology Journal Club

December 2012
Wed, 12/5/12 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Amanda Mason
Finkbeiner Lab
Paper: Gu, Y., M. Arruda-Carvalho, et al. (2012). "Optical controlling reveals time-dependent roles for adult-born dentate granule cells." Nat Neurosci 15(12): 1700-1706.

Tue, 12/11/12 Noon – Parnassus room TBA
Stem Cell Journal Club
Presenter: Justin Ellis
Rowitch Lab
Title A New Paradigm Of Brain Development?
Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex. Santos J. Franco et al. Science 337, 746 (2012); DOI: 10.1126/science.1223616

Wed, 12/19/12 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Matt Donne
Rock Lab
"Fish get a leg up: Hoxd13s Contribution to the Evolution of Vertebrate Appendages"
Paper: Hoxd13 Contribution to the Evolution of Vertebrate Appendages Renata Freitas,1,2 Carlos Go´ mez Marž´n,1 Jonathan Mark Wilson,1 Fernando Casares,1,* and Jose´ Luis Go´ mez-Skarmeta1,* Developmental Cell 23, 1219­1229, December 11, 2012
http://ac.els-cdn.com/S1534580712004789/1-s2.0-S1534580712004789-main.pd...

January 2013
Tue, 1/8/13 Noon – Parnassus room TBA
Stem Cell Journal Club
Presenter: Jake Freimer
Blelloch Lab
Paper: Tet1 controls meiosis by regulating meiotic gene expression. Nature, 2012 Dec 20;492(7429):443-7. doi: 10.1038/nature11709. Epub 2012 Nov 14
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11709.html

note date change
Wed, 1/23/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Marie La Russa
Blelloch Lab
Paper: Asymmetrically modified nucleosomes. Cell. 2012 Sep 28;151(1):181-93. doi: 10.1016/j.cell.2012.09.002
http://www.ncbi.nlm.nih.gov/pubmed/23021224

Febuary 2013
Wed, 2/6/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Nicole Stone
Paper: Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration.  Nat Cell Biol. 2012 Dec 23;15(2):222-8. doi: 10.1038/ncb2659. Epub 2013 Jan 13.
Srivastava Lab

Wed, 2/20/13 5:45 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Becky Andersen
Lim Lab
"Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment".

March 2013
Wed, 3/6/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Liz Wheatley
Villeda Lab
Title: Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition–like mechanism
Yasuhiro Itoh1, Yasunobu Moriyama1, Tsuyoshi Hasegawa1, Takaho A Endo2, Tetsuro Toyoda2 & Yukiko Gotoh1 Nature Neuroscience  2013, published online 24 February 2013

Tue, 3/12/13 Noon – Parnassus room N-217
Stem Cell Journal Club
Presenter: Ysbrand Nusse
Title “Houseguests from Hell: Leprosy Reprograms Its Niche”
Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection.  Masaki T, Qu J, Cholewa-Waclaw J, Burr K, Raaum R, Rambukkana A.  Cell. 17 Jan 2013. 152 (1): 51-67. 

Wed, 3/20/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Mikhail Binnewies
Krummel Lab
Title: Intestinal label-retaining cells are secretory precursors expressing Lgr5.
Buczacki SJ, Zecchini HI, Nicholson AM, Russell R, Vermeulen L, Kemp R, Winton DJ. Source Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Nature. 2013 Mar 7;495(7439):65-9. doi: 10.1038/nature11965. Epub 2013 Feb 27.

April 2013
Wed, 4/3/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Andy Norman
Reiter Lab
Title: Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice. Xiaoning Han, Michael Chen, Fushun Wang, Martha Windrew, Su Wang,
Cell Stem Cell. Volume 12, Issue 3, 7 March 2013, Pages 342–353

Tue, 4/9/13 Noon – Parnassus room TBA
Stem Cell Journal Club
Presenter: Kate Woronowicz
Schneider Lab
Title "Restoration of Vision After Transplantation of Photoreceptors"
Pearson RA, Barber AC, Rizzi M, Hippert C, Xue T, West EL, Duran Y, Smith AJ, Chuang JZ, Azam SA,
Luhmann UFO, Benucci A, Sung CH, Bainbridge JW, Carandini M, Yau K-W, Sowden JC & Ali RR. 

Wed, 4/17/13 5:45 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Svetlana Keylin
Kajimura Lab
Title "Characterization of the adipocyte cellular lineage in vivo".
http://www.nature.com/ncb/journal/v15/n3/full/ncb2696.html

May 2013
Wed, 5/1/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Matt George
Bruneau Lab
Title: Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes. Warren A. Whyte,1,4 David A. Orlando,1,4 Denes Hnisz,1,4 Brian J. Abraham,1 Charles Y. Lin,1,2 Michael H. Kagey,1 Peter B. Rahl,1 Tong Ihn Lee,1 and Richard A. Young1,3,*1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA 2Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA 3Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

Tue, 5/14/13 Noon – Parnassus room TBA
Stem Cell Journal Club
Presenter: Pankaj Sahai
Nystul Lab
Title : Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.
Andrea Flesken-Nikitin1, Chang-Il Hwang1, Chieh-Yang Cheng1, Tatyana V. Michurina2,3, Grigori Enikolopov2,3
& Alexander Yu. Nikitin1
Nature, 495, 241-245 (14 March 2013)
http://www.nature.com/nature/journal/v495/n7440/pdf/nature11979.pdf

Wed, 5/15/13 5:30 p.m. Mission Bay CVRI SC159
Developmental Biology Journal Club
Presenter: Gabe McKinsey
Rubenstein Lab
Title "From Small Beginnings Come Great Things: Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium".

June 2013
Friday 6/7/12 - Developmental Biology Symposium
9:00 a.m.-6:00 p.m. Mission Bay, Byer Auditorium